Assay Detail
Binding
CHEMBL4814448
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FAK in human OVCAR8 cells assessed as reduction in phosphorylation at Y397 residue incubated for 30 mins by Western blot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | OVCAR-8 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Progress in the Development of Small Molecular Inhibitors of Focal Adhesion Kinase (FAK).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.82 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4742157 | GSK-2256098 | 2.0 | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4742157 | GSK-2256098 | IC50 | = | 15.0 | nM | 7.82 |