Assay Detail
Functional
CHEMBL4814679
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiamoebic activity against Entamoeba histolytica HK9 ATCC 30015 incubated for 72 hrs by trypan blue staining based assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Entamoeba histolytica |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.97 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4795316 | — | — | 1 | 6.02 |
| CHEMBL137 | METRONIDAZOLE | 4.0 | 1 | 5.28 |
| CHEMBL4786380 | — | — | 1 | 5.27 |
| CHEMBL1362047 | — | — | 1 | 4.25 |
| CHEMBL236696 | — | — | 1 | 4.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4795316 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL137 | METRONIDAZOLE | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL4786380 | — | IC50 | = | 5320.0 | nM | 5.27 |
| CHEMBL1362047 | — | IC50 | = | 55700.0 | nM | 4.25 |
| CHEMBL236696 | — | IC50 | = | 94260.0 | nM | 4.03 |