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Assay Detail

CHEMBL4814953

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of anti-human CD3/CD28/mAbs-stimulated human T-lymphocutes proliferation after 72 hrs by CFSE staining based flow cytometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type T-cell
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Cyclotides from Brazilian <i>Palicourea sessilis</i> and Their Effects on Human Lymphocytes.
Pinto MEF, Chan LY, Koehbach J, Devi S, Gründemann C, Gruber CW, Gomes M, Bolzani VS, Cilli EM, Craik DJ.
J Nat Prod (2021) 84 : 81 -90
PubMed 33397096 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.72 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4211294 1 5.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4211294 IC50 = 1900.0 nM 5.72