Assay Detail
Functional
CHEMBL4815641
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Cytotoxicity against human NCI-H460 cells assessed as cell growth inhibition measured after 24 to 72 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic Physalins from Aeroponically Grown <i>Physalis acutifolia</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.13 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.30 |
| CHEMBL4855552 | — | — | 1 | 6.22 |
| CHEMBL4850591 | — | — | 1 | 6.22 |
| CHEMBL504404 | PHYSALIN B | — | 1 | 6.05 |
| CHEMBL504910 | — | — | 1 | 6.00 |
| CHEMBL4875654 | — | — | 1 | 5.92 |
| CHEMBL4869335 | — | — | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL4855552 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4850591 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL504404 | PHYSALIN B | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL504910 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4875654 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4869335 | — | IC50 | = | 6500.0 | nM | 5.19 |