Assay Detail
Binding
CHEMBL4815903
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Competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase using alpha-PNPG as substrate incubated for 30 mins by Lineweaver-Burk plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2,5-Disubstituted furan derivatives containing 1,3,4-thiadiazole moiety as potent α-glucosidase and E. coli β-glucuronidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.30 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4855744 | — | — | 1 | 7.30 |
| CHEMBL404271 | ACARBOSE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4855744 | — | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL404271 | ACARBOSE | Ki | = | 378100.0 | nM | - |