Assay Detail
Binding
CHEMBL4815907
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Uncompetitive inhibition of recombinant Escherichia coli beta-glucosidase expressed in Escherichia coli BL2(DE3) using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Burk plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2,5-Disubstituted furan derivatives containing 1,3,4-thiadiazole moiety as potent α-glucosidase and E. coli β-glucuronidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.26 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1113 | AMOXAPINE | 4.0 | 1 | 7.30 |
| CHEMBL4854113 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1113 | AMOXAPINE | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL4854113 | — | Ki | = | 60.0 | nM | 7.22 |