Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4816174

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against HUVEC incubated for 6 hrs by inverted microscopic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type HUVEC
Confidence 1 — Organism
Curated By Autocuration

Target

HUVEC (CHEMBL613979)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities.
Zhu H, Li W, Shuai W, Liu Y, Yang L, Tan Y, Zheng T, Yao H, Xu J, Zhu Z, Yang DH, Chen ZS, Xu S.
Eur J Med Chem (2021) 216 : 113316 -113316
PubMed 33676300 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.92 6.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4866085 1 6.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4866085 IC50 = 120.0 nM 6.92