Assay Detail
Functional
CHEMBL4817639
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Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MGC-803 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.57 | 4.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4865016 | — | — | 1 | 4.57 |
| CHEMBL4860176 | — | — | 1 | - |
| CHEMBL1461372 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4865016 | — | IC50 | = | 27160.0 | nM | 4.57 |
| CHEMBL4860176 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL1461372 | — | IC50 | > | 50000.0 | nM | - |