Assay Detail
Functional
CHEMBL4817812
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Antiviral activity against Zaire ebola virus infected in African green monkey Vero cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Zaire ebolavirus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enantiomeric 4'-truncated 6'-fluoro-3-deazaneplanocin and its 3-bromo derivative: Synthesis and antiviral properties, including Ebola and Marburg.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.02 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4874341 | — | — | 1 | 6.96 |
| CHEMBL4853962 | — | — | 1 | 6.92 |
| CHEMBL221722 | FAVIPIRAVIR | 4.0 | 1 | 4.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4874341 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL4853962 | — | EC50 | = | 120.0 | nM | 6.92 |
| CHEMBL221722 | FAVIPIRAVIR | EC50 | = | 66000.0 | nM | 4.18 |