Assay Detail
Binding
CHEMBL4818032
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human ERG
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Voltage-gated inwardly rectifying potassium channel KCNH2 (CHEMBL240) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of N-amido-phenylsulfonamide derivatives as novel microsomal prostaglandin E<sub>2</sub> synthase-1 (mPGES-1) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.15 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4848472 | — | — | 1 | 5.28 |
| CHEMBL4864480 | — | — | 1 | 5.02 |
| CHEMBL4870406 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4848472 | — | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL4864480 | — | IC50 | = | 9600.0 | nM | 5.02 |
| CHEMBL4870406 | — | IC50 | > | 10000.0 | nM | - |