Assay Detail
ADMET
CHEMBL4819448
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Cytotoxicity against human HL7702 cells incubated for 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | L02 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances of podophyllotoxin/epipodophyllotoxin hybrids in anticancer activity, mode of action, and structure-activity relationship: An update (2010-2020).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.14 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4847670 | — | — | 1 | 6.52 |
| CHEMBL4869119 | — | — | 1 | 6.52 |
| CHEMBL61 | PODOFILOX | 4.0 | 1 | 5.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4847670 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4869119 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL61 | PODOFILOX | IC50 | = | 4310.0 | nM | 5.37 |