Assay Detail
Binding
CHEMBL4820030
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Inhibition of human ERAP2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Endoplasmic reticulum aminopeptidase 2 (CHEMBL5043) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Modulators of hERAP2 discovered by high-throughput screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.48 | 4.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4101200 | — | — | 1 | 4.48 |
| CHEMBL3416725 | — | — | 1 | - |
| CHEMBL3416733 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4101200 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL3416725 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3416733 | — | IC50 | = | 755000.0 | nM | - |