Assay Detail
Binding
CHEMBL4821479
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Binding affinity to human D5R
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Radioligand and computational insight in structure - Activity relationship of saccharin derivatives being ipsapirone and revospirone analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 13 | 6.03 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL238915 | — | — | 1 | 6.64 |
| CHEMBL238917 | — | — | 1 | 5.95 |
| CHEMBL394110 | — | — | 1 | 5.79 |
| CHEMBL238916 | — | — | 1 | 5.75 |
| CHEMBL4853248 | — | — | 1 | - |
| CHEMBL4849583 | — | — | 1 | - |
| CHEMBL2107024 | REVOSPIRONE | 2.0 | 1 | - |
| CHEMBL8412 | IPSAPIRONE | 2.0 | 1 | - |
| CHEMBL4540404 | — | — | 1 | - |
| CHEMBL4439795 | — | — | 1 | - |
| CHEMBL4463030 | — | — | 1 | - |
| CHEMBL4565558 | — | — | 1 | - |
| CHEMBL4470487 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL238915 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL238917 | — | Ki | = | 1132.0 | nM | 5.95 |
| CHEMBL394110 | — | Ki | = | 1629.0 | nM | 5.79 |
| CHEMBL238916 | — | Ki | = | 1756.0 | nM | 5.75 |
| CHEMBL4853248 | — | Ki | - | — | - | |
| CHEMBL4849583 | — | Ki | - | — | - | |
| CHEMBL2107024 | REVOSPIRONE | Ki | - | — | - | |
| CHEMBL8412 | IPSAPIRONE | Ki | - | — | - | |
| CHEMBL4540404 | — | Ki | - | — | - | |
| CHEMBL4439795 | — | Ki | - | — | - | |
| CHEMBL4463030 | — | Ki | - | — | - | |
| CHEMBL4565558 | — | Ki | - | — | - | |
| CHEMBL4470487 | — | Ki | - | — | - |