Assay Detail
Binding
CHEMBL4822216
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Inhibition of beta 5 chymotrypsin-like activity (unknown origin) using Suc-LLVY-AMC as substrate for 90 mins by fluorescence based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of selective fragment-sized immunoproteasome inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.16 | 4.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4858322 | — | — | 1 | 4.35 |
| CHEMBL4848759 | — | — | 1 | 4.09 |
| CHEMBL4865958 | — | — | 1 | 4.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4858322 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL4848759 | — | IC50 | = | 81000.0 | nM | 4.09 |
| CHEMBL4865958 | — | IC50 | = | 93000.0 | nM | 4.03 |