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Assay Detail

CHEMBL4822358

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against Plasmodium falciparum 7G8
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

A trio of quinoline-isoniazid-phthalimide with promising antiplasmodial potential: Synthesis, in-vitro evaluation and heme-polymerization inhibition studies.
Rani A, Sharma A, Legac J, Rosenthal PJ, Singh P, Kumar V.
Bioorg Med Chem (2021) 39 : 116159 -116159
PubMed 33895706 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.38 7.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL390195 1 7.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL390195 IC50 = 42.2 nM 7.38