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Assay Detail

CHEMBL4822552

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of ASCT2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Neutral amino acid transporter B(0) (CHEMBL3562162)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design and evaluation of 1,2,3-dithiazoles and fused 1,2,4-dithiazines as anti-cancer agents.
Maffuid KA, Koyioni M, Torrice CD, Murphy WA, Mewada HK, Koutentis PA, Crona DJ, Asquith CRM.
Bioorg Med Chem Lett (2021) 43 : 128078 -128078
PubMed 33951490 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.09 5.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4867768 1 5.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4867768 IC50 = 8100.0 nM 5.09