Assay Detail
ADMET
CHEMBL4822653
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Cytotoxicity against human L02 cells by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | L02 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pulchinenosides: Correlation of surface activity-cytotoxicity and hepatocyte apoptosis mechanism study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.88 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL444941 | HEDERACOLCHISIDE A1 | — | 1 | 5.15 |
| CHEMBL4447568 | — | — | 1 | 5.13 |
| CHEMBL4860704 | — | — | 1 | 5.02 |
| CHEMBL447565 | ALPHA-HEDERIN | — | 1 | 4.68 |
| CHEMBL479310 | HEDERACOLCHISIDE A | — | 1 | 4.67 |
| CHEMBL502407 | — | — | 1 | 4.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL444941 | HEDERACOLCHISIDE A1 | IC50 | = | 7130.0 | nM | 5.15 |
| CHEMBL4447568 | — | IC50 | = | 7490.0 | nM | 5.13 |
| CHEMBL4860704 | — | IC50 | = | 9570.0 | nM | 5.02 |
| CHEMBL447565 | ALPHA-HEDERIN | IC50 | = | 20980.0 | nM | 4.68 |
| CHEMBL479310 | HEDERACOLCHISIDE A | IC50 | = | 21120.0 | nM | 4.67 |
| CHEMBL502407 | — | IC50 | = | 23070.0 | nM | 4.64 |