Assay Detail
Binding
CHEMBL4822996
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of N-terminal His-tagged human JMJD7 (1 to 316 residues) expressed in Escherichia coli BL21 (DE3) using peptide substrate DRG (16 to 30) measured by flourescence polarisation competition assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (CHEMBL4879430) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of JMJD7 inhibitors with the aid of virtual screening and bioactivity evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.42 | 5.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4846929 | — | — | 1 | 5.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4846929 | — | IC50 | = | 3800.0 | nM | 5.42 |