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Assay Detail

CHEMBL4822998

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human SK-BR-3 cells assessed as growth inhibition measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SK-BR-3
Confidence 1 — Organism
Curated By Autocuration

Target

SK-BR-3 (CHEMBL613834)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of JMJD7 inhibitors with the aid of virtual screening and bioactivity evaluation.
Zhang W, Li K, Wang T, Wu M, Li L.
Bioorg Med Chem Lett (2021) 45 : 128139 -128139
PubMed 34048880 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.88 4.88

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4846929 1 4.88

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4846929 IC50 = 13260.0 nM 4.88