Assay Detail
Binding
CHEMBL4823527
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Competitive inhibition of pig pancreatic lipase type 2 using varying concentrations of p-nitrophenyl butyrate as substrate measured every 1 min for 30 mins by Lineweaver-Burk plot analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Natural Isoflavones and Semisynthetic Derivatives as Pancreatic Lipase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 4.08 | 4.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44 | GENISTEIN | 2.0 | 1 | 4.10 |
| CHEMBL4780482 | — | — | 1 | 4.05 |
| CHEMBL8145 | DAIDZEIN | 2.0 | 1 | - |
| CHEMBL242341 | FORMONONETIN | 2.0 | 1 | - |
| CHEMBL4878391 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44 | GENISTEIN | Ki | = | 80000.0 | nM | 4.10 |
| CHEMBL4780482 | — | Ki | = | 90000.0 | nM | 4.05 |
| CHEMBL8145 | DAIDZEIN | Ki | = | 300000.0 | nM | - |
| CHEMBL242341 | FORMONONETIN | Ki | = | 640000.0 | nM | - |
| CHEMBL4878391 | — | Ki | = | 320000.0 | nM | - |