Assay Detail
Binding
CHEMBL4824767
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of calcineurin (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Vomifoliol isolated from mangrove plant Ceriops tagal inhibits the NFAT signaling pathway with CN as the target enzyme in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.66 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463088 | BLUMENOL A | — | 1 | 4.82 |
| CHEMBL160 | CYCLOSPORINE | 4.0 | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463088 | BLUMENOL A | IC50 | = | 15130.0 | nM | 4.82 |
| CHEMBL160 | CYCLOSPORINE | IC50 | = | 31350.0 | nM | 4.50 |