Assay Detail
ADMET
CHEMBL4826381
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Cytotoxicity against human HMEC-1 cells assessed as growth inhibition after 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HMEC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Water-Soluble Heliomycin Derivatives to Target i-Motif DNA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.35 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.00 |
| CHEMBL1320139 | HELIOMYCIN | 2.0 | 1 | 6.30 |
| CHEMBL4854641 | — | — | 1 | 6.16 |
| CHEMBL4851019 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1320139 | HELIOMYCIN | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4854641 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL4851019 | — | IC50 | = | 1200.0 | nM | 5.92 |