Assay Detail
Binding
CHEMBL4828008
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant FLAG-tagged HDAC2 expressed in Sf9 cells incubated for 30 mins by Fluor De Lys assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel Histone Deacetylase Inhibitors for Treating HIV Infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.90 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4861467 | — | — | 1 | 9.52 |
| CHEMBL4862152 | — | — | 1 | 9.15 |
| CHEMBL4861271 | — | — | 1 | 8.70 |
| CHEMBL4873493 | — | — | 1 | 8.66 |
| CHEMBL4862556 | — | — | 1 | 8.49 |
| CHEMBL4864510 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4861467 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL4862152 | — | IC50 | = | 0.7 | nM | 9.15 |
| CHEMBL4861271 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL4873493 | — | IC50 | = | 2.2 | nM | 8.66 |
| CHEMBL4862556 | — | IC50 | = | 3.2 | nM | 8.49 |
| CHEMBL4864510 | — | IC50 | < | 1.5 | nM | - |