Assay Detail
Binding
CHEMBL4828010
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Inhibition of human HDAC6 incubated for 30 mins by Fluor De Lys assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel Histone Deacetylase Inhibitors for Treating HIV Infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.08 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4861271 | — | — | 1 | 7.35 |
| CHEMBL4862556 | — | — | 1 | 7.13 |
| CHEMBL4861467 | — | — | 1 | 7.12 |
| CHEMBL4873493 | — | — | 1 | 7.08 |
| CHEMBL4862152 | — | — | 1 | 6.95 |
| CHEMBL4864510 | — | — | 1 | 6.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4861271 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL4862556 | — | IC50 | = | 74.0 | nM | 7.13 |
| CHEMBL4861467 | — | IC50 | = | 76.0 | nM | 7.12 |
| CHEMBL4873493 | — | IC50 | = | 83.0 | nM | 7.08 |
| CHEMBL4862152 | — | IC50 | = | 113.0 | nM | 6.95 |
| CHEMBL4864510 | — | IC50 | = | 144.0 | nM | 6.84 |