Assay Detail
Functional
CHEMBL4828891
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania amazonensis (MHOM/BR/73/M2269) promastigotes assessed as inhibition of parasite growth measured after 24 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania amazonensis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Mechanistic Insights into the Leishmanicidal and Bactericidal Activities of Batroxicidin, a Cathelicidin-Related Peptide from a South American Viper (<i>Bothrops atrox</i>).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.79 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | 4.0 | 1 | 7.62 |
| CHEMBL4861276 | — | — | 1 | 5.31 |
| CHEMBL4864681 | — | — | 1 | 5.17 |
| CHEMBL4846717 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | EC50 | = | 24.0 | nM | 7.62 |
| CHEMBL4861276 | — | EC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL4864681 | — | EC50 | = | 6740.0 | nM | 5.17 |
| CHEMBL4846717 | — | EC50 | = | 8860.0 | nM | 5.05 |