Assay Detail
Binding
CHEMBL4829628
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Inhibition of human alpha-glucosidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-l-ido-DNJ derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.93 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4856375 | — | — | 1 | 6.00 |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4856375 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 1400.0 | nM | 5.85 |