Assay Detail
Binding
CHEMBL4830581
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human 5HT2C receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis and biological evaluation of pyridinylmethylenepiperidine derivatives as potent 5-HT<sub>1F</sub> receptor agonists for migraine therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.15 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4851044 | — | — | 1 | 5.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4851044 | — | IC50 | = | 7060.5 | nM | 5.15 |