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Assay Detail

CHEMBL4830758

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ADMET
Cytotoxicity against human L02 cells assessed as reduction in cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type L02
Confidence 1 — Organism
Curated By Autocuration

Target

L02 (CHEMBL4296457)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
Eur J Med Chem (2021) 225 : 113790 -113790
PubMed 34454126 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.25 6.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4874942 1 6.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4874942 IC50 = 556.0 nM 6.25