Assay Detail
Functional
CHEMBL4832181
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human KURAMOCHI cells assessed as inhibition of cell viability for 96 hrs by cell titre glo luminescence assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KURAMOCHI |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.05 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4870906 | — | — | 1 | 5.48 |
| CHEMBL4866490 | — | — | 1 | 5.43 |
| CHEMBL4852896 | — | — | 1 | 5.16 |
| CHEMBL4282040 | — | — | 1 | 4.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4870906 | — | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL4866490 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL4852896 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL4282040 | — | IC50 | = | 75000.0 | nM | 4.12 |