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Assay Detail

CHEMBL4832334

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Functional
Antiproliferative activity against human SW480 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SW480
Confidence 1 — Organism
Curated By Autocuration

Target

SW480 (CHEMBL612544)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of a potent and selective inhibitor of histone lysine demethylase KDM4D.
Fang Z, Liu Y, Zhang R, Chen Q, Wang T, Yang W, Fan Y, Yu C, Xiang R, Yang S.
Eur J Med Chem (2021) 223 : 113662 -113662
PubMed 34237635 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.97 4.97

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4850758 1 4.97

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4850758 IC50 = 10700.0 nM 4.97