Assay Detail
Binding
CHEMBL4833103
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inverse agonist activity at mouse RORC ligand binding domain incubated for 30 mins by scintillation proximity binding assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.00 | 7.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4864604 | — | — | 1 | 7.08 |
| CHEMBL4562895 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4864604 | — | IC50 | = | 84.0 | nM | 7.08 |
| CHEMBL4562895 | — | IC50 | = | 120.0 | nM | 6.92 |