Assay Detail
Functional
CHEMBL4833993
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Antileishmanial activity against promastigote form of wild-type Leishmania donovani
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.00 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4874673 | — | — | 1 | 6.39 |
| CHEMBL2347704 | ACOZIBOROLE | 2.0 | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4874673 | — | EC50 | = | 411.0 | nM | 6.39 |
| CHEMBL2347704 | ACOZIBOROLE | EC50 | = | 2500.0 | nM | 5.60 |