Assay Detail
Functional
CHEMBL4835148
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Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum K1 measured after 72 hrs by lactate dehydrogenase assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiplasmodial Oleanane Triterpenoids from <i>Terminalia albida</i> Root Bark.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.17 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 6.82 |
| CHEMBL4873325 | — | — | 1 | 5.21 |
| CHEMBL4864142 | — | — | 1 | 5.21 |
| CHEMBL4869593 | — | — | 1 | 5.16 |
| CHEMBL4876283 | — | — | 1 | 5.04 |
| CHEMBL4852152 | — | — | 1 | 5.00 |
| CHEMBL4853624 | — | — | 1 | 4.95 |
| CHEMBL4851778 | — | — | 1 | 4.86 |
| CHEMBL4854639 | — | — | 1 | 4.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL4873325 | — | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL4864142 | — | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL4869593 | — | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL4876283 | — | IC50 | = | 9100.0 | nM | 5.04 |
| CHEMBL4852152 | — | IC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL4853624 | — | IC50 | = | 11300.0 | nM | 4.95 |
| CHEMBL4851778 | — | IC50 | = | 13900.0 | nM | 4.86 |
| CHEMBL4854639 | — | IC50 | = | 48500.0 | nM | 4.31 |