Assay Detail
Functional
CHEMBL4838558
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anti-HIV activity against HIV-2 isolate ROD infected in human MT4 cells assessed as protection against virus-induced cytopathicity measured after 5 days by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | MT4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and in vitro antitumour activity of 4(R)-methyl-3-O-phosphonomethyl-α-l-threose nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.39 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3938729 | — | — | 1 | 5.60 |
| CHEMBL3976812 | — | — | 1 | 5.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3938729 | — | EC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL3976812 | — | EC50 | = | 6590.0 | nM | 5.18 |