Assay Detail
Binding
CHEMBL4839005
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of wild type GNAQ (unknown origin) expressed in CRISPR/Cas9 engineered HEK293 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Guanine nucleotide-binding protein G(q) subunit alpha (CHEMBL3286079) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Feature-Based Molecular Networking for the Targeted Identification of G<sub>q</sub>-Inhibiting FR900359 Derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.56 | 5.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4873047 | — | — | 1 | 5.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4873047 | — | IC50 | = | 2754.23 | nM | 5.56 |