Assay Detail
Functional
CHEMBL4840219
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against asexual late stage (IV-V) Plasmodium falciparum 3D7 gametocytes expressing CBG99 luciferase infected in human red blood cells assessed as reduction in gametocyte viability measured after 72 hrs by luminescence based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.98 | 4.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4854616 | — | — | 1 | 4.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4854616 | — | IC50 | = | 10400.0 | nM | 4.98 |