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Assay Detail

CHEMBL4841158

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MDA-MB-231 cells assessed as cell viability measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
Li J, Yan Z, Li H, Shi Q, Ahire V, Zhang S, Nimishetti N, Yang D, Allen TD, Zhang J.
J Nat Prod (2021) 84 : 2312 -2320
PubMed 34406008 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.13 5.13

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1235966 SCOULERINE 1 5.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1235966 SCOULERINE IC50 = 7324.0 nM 5.13