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Assay Detail

CHEMBL4841174

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of sEH (unknown origin) expressed in baculovirus expression system incubated for 1 hr
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Bifunctional epoxide hydrolase 2 (CHEMBL2409)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Configurational Assignment of a Flexible Benzo[<i>g</i>]isochromene Stereodiad from <i>Rubia philippinensis</i> and Inhibition of Soluble Epoxide Hydrolase Activity.
Quan KT, Park I, Kim CS, Yoshida W, Ferreira D, Thuong PT, Kim YH, Na M, Oh J.
J Nat Prod (2021) 84 : 2594 -2599
PubMed 34427436 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.72 9.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL215387 1 9.22
CHEMBL4873654 1 6.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL215387 IC50 = 0.6 nM 9.22
CHEMBL4873654 IC50 = 600.0 nM 6.22