Assay Detail
Functional
CHEMBL4841296
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human TMD8 cells assessed as reduction in cell proliferation measured after 3 to 7 days by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | TMD8 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.58 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4786559 | — | — | 1 | 7.82 |
| CHEMBL4876497 | — | — | 1 | 7.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4786559 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL4876497 | — | IC50 | = | 46.0 | nM | 7.34 |