Assay Detail
Binding
CHEMBL4841377
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of actomyosin ATPase activity in bovine cardiac myofibrils assessed as reduction in inorganic phosphate release using ATP as substrate preincubated for 30 mins in presence of pCa 4.5 followed by substrate addition by malachite green based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A Potent Fluorescent Reversible-Covalent Inhibitor of Cardiac Muscle Contraction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.96 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3582415 | — | — | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3582415 | — | IC50 | = | 11.0 | nM | 7.96 |