Assay Detail
Binding
CHEMBL4841382
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to calcium saturated His-tagged cNTnC (1 to 90 residues)- cTnI (136 to 163 residues) A-Cys chimeric protein harboring C35S/C84S double mutant (unknown origin) assessed as dissociation constant by flourescence spectroscopy analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A Potent Fluorescent Reversible-Covalent Inhibitor of Cardiac Muscle Contraction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.35 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3582415 | — | — | 1 | 7.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3582415 | — | Kd | = | 45.0 | nM | 7.35 |