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Assay Detail

CHEMBL4841992

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of ACE (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y<sub>4</sub> Receptor Ligands Results in Picomolar Binding Constants.
Konieczny A, Conrad M, Ertl FJ, Gleixner J, Gattor AO, Grätz L, Schmidt MF, Neu E, Horn AHC, Wifling D, Gmeiner P, Clark T, Sticht H, Keller M.
J Med Chem (2021) 64 : 16746 -16769
PubMed 34748345 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.60 7.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1168 RAMIPRIL 4.0 1 7.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1168 RAMIPRIL IC50 = 25.12 nM 7.60