Assay Detail
Functional
CHEMBL4842451
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Omsk hemorrhagic fever virus infected in pig PEK cells assessed as reduction in virus plaque formation preincubated with virus for 1 hr followed by cell infection and measured after 1 hr by crystal violet staining based assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Omsk hemorrhagic fever virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Omsk hemorrhagic fever virus (CHEMBL4888474) ↗| Type | ORGANISM |
| Organism | Omsk hemorrhagic fever virus |
Publication
Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 5.04 | 5.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4870983 | — | — | 1 | 5.51 |
| CHEMBL4875977 | — | — | 1 | 5.35 |
| CHEMBL4865141 | — | — | 1 | 5.30 |
| CHEMBL4857025 | — | — | 1 | 5.14 |
| CHEMBL4858629 | — | — | 1 | 4.82 |
| CHEMBL4872020 | — | — | 1 | 4.67 |
| CHEMBL4878050 | — | — | 1 | 4.48 |
| CHEMBL4846008 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4870983 | — | EC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL4875977 | — | EC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL4865141 | — | EC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL4857025 | — | EC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL4858629 | — | EC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL4872020 | — | EC50 | = | 21400.0 | nM | 4.67 |
| CHEMBL4878050 | — | EC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL4846008 | — | EC50 | > | 50000.0 | nM | - |