Assay Detail
Functional
CHEMBL4843400
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Antiviral activity against Dengue virus 2 infected in human A549 cells assessed as reduction in viral titer production measured after 48 hrs by plaque reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 2 |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.09 | 6.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4437334 | — | — | 1 | 6.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4437334 | — | EC50 | = | 810.0 | nM | 6.09 |