Assay Detail

CHEMBL4880156

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Binding

Immunoblot method to monitor prenylation inhibition of Ras

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Data for DCP probe ABT-100

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	9.14	9.14

Assay Parameters

Parameter	Type	Value	Units	Text
Assay publication	Assay publication	-	—	PMID: 16222147
Target protein type	Target protein type	-	—	NIH 3T3 Ras

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4586794	ABT-100	—	2	9.14

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4586794	ABT-100	EC50	=	0.73	nM	9.14
CHEMBL4586794	ABT-100	EC50	=	0.73	nM	9.14