Assay Detail
Binding
CHEMBL4880934
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cell-based assay with CellTiter-Glo readout for ATP production with SLC2A4
2
Total Activities
2
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Solute carrier family 2, facilitated glucose transporter member 4 (CHEMBL5874) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe BAY-876
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.44 | 6.57 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 27552707 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4448899 | BAY-876 | — | 1 | 6.57 |
| CHEMBL4552180 | BAY-588 | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4448899 | BAY-876 | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL4552180 | BAY-588 | IC50 | = | 500.0 | nM | 6.30 |