Assay Detail
Binding
CHEMBL4880938
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Cellular luciferase reporter assay using the SN12C-MEF2-luc cell line and ONE-Glo
2
Total Activities
2
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | SN12C |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe BAY-885
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.95 | 6.94 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 30563338 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4445670 | BAY-885 | — | 1 | 6.94 |
| CHEMBL4455582 | BAY-693 | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4445670 | BAY-885 | IC50 | = | 115.0 | nM | 6.94 |
| CHEMBL4455582 | BAY-693 | IC50 | = | 11000.0 | nM | 4.96 |