Assay Detail

CHEMBL4880943

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Functional

Proliferation assay: SN12C (renal cell carcinoma)

ChEMBL ↗

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Target

SN12C (CHEMBL614054) ↗

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Primary target SN12C

CHEMBL614054

Anchored from Assay target.

Protein identity SN12C

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	SN12C
Confidence	1 — Organism
Curated By	Autocuration

Target

SN12C (CHEMBL614054) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Data for DCP probe BAY-885

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.53	4.53

Assay Parameters

Parameter	Type	Value	Units	Text
Additional information	Additional information	-	—	Cell viability was determined with a CellTiter-Glo® luminescent assay

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4455582	BAY-693	—	1	4.53

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4455582	BAY-693	IC50	=	29300.0	nM	4.53