Assay Detail

CHEMBL4881308

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Binding

Inhibition of platelet aggregation (human plasma, thrombin)

ChEMBL ↗

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Target

Platelet (CHEMBL4296519) ↗

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Primary target Platelet

CHEMBL4296519

Anchored from Assay target.

Protein identity Platelet

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Tissue	Plasma
Cell Type	Platelet
Confidence	1 — Organism
Curated By	Autocuration

Target

Platelet (CHEMBL4296519) ↗

Type

CELL-LINE

Publication

Data for DCP probe BAY-386

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.85	6.85

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4630644	BAY-386	—	1	6.85

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4630644	BAY-386	IC50	=	140.0	nM	6.85