Assay Detail

CHEMBL4882232

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Binding

Scintillation Proximity Assay binding

ChEMBL ↗

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Target

C-C chemokine receptor type 1 (CHEMBL2413) ↗

Open DB target context

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C-C chemokine receptor type 1 (CHEMBL2413) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target C-C chemokine receptor type 1

CHEMBL2413

Anchored from Assay target.

Protein identity C-C chemokine receptor type 1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

C-C chemokine receptor type 1 (CHEMBL2413) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe BI 639667

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.27	8.27

Assay Parameters

Parameter	Type	Value	Units	Text
Additional information	Additional information	-	—	CCR1 binding affinity

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4456123	BI 639667	1.0	1	8.27

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4456123	BI 639667	IC50	=	5.4	nM	8.27